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Exflagellation usually happens in the sexual cycle of the parasite in the mosquitos guts. However, when the condition is right, it can occur in vitro in an EDTA sample.
Diagnosis: Acute Promyelocytic Leukemia with t(15;17) and PML/RARA
Acknowledgement: Virtual slide provided here with the permission from the Department of Hematopathology, Vancouver General Hospital, Vancouver, BC, Canada.